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Post subject: Legionnaires' disease -Part #2  PostPosted: Oct 11, 2005 - 07:44 AM

<Legionellosis is an infection caused by the bacterium Legionella pneumophila. The disease has two distinct forms:

<Legionnaires' disease, the more severe form of infection which includes pneumonia, and

<Pontiac fever, a milder illness.

<Legionnaires' disease acquired its name in 1976 when an outbreak of pneumonia occurred among persons attending a convention of the American Legion in Philadelphia. Later, the bacterium causing the illness was named Legionella.

What is Legionnaires’ disease?

Legionnaires’ disease (LEE-juh-nares) is caused by a type of bacteria called Legionella. The bacteria got its name in 1976, when many people who went to a Philadelphia convention of the American Legion suffered from an outbreak of this disease, a type of pneumonia (lung infection). Although this type of bacteria was around before1976, more illness from Legionnaires’ disease is being detected now. This is because we are now looking for this disease whenever a patient has pneumonia.

Each year, between 8,000 and 18,000 people are hospitalized with Legionnaires' disease in the U.S. However, many infections are not diagnosed or reported, so this number may be higher. More illness is usually found in the summer and early fall, but it can happen any time of year.

What are the symptoms of Legionnaires’ disease?

Legionnaires' disease can have symptoms like many other forms of pneumonia, so it can be hard to diagnose at first. Signs of the disease can include: a high fever, chills, and a cough. Some people may also suffer from muscle aches and headaches. Chest X-rays are needed to find the pneumonia caused by the bacteria, and other tests can be done on sputum (phlegm), as well as blood or urine to find evidence of the bacteria in the body.

These symptoms usually begin 2 to 14 days after being exposed to the bacteria.

A milder infection caused by the same type of Legionella bacteria is called Pontiac Fever. The symptoms of Pontiac Fever usually last for 2 to 5 days and may also include fever, headaches, and muscle aches; however, there is no pneumonia. Symptoms go away on their own without treatment and without causing further problems.

Pontiac Fever and Legionnaires’ disease may also be called “Legionellosis” (LEE-juh-nuh-low-sis) separately or together.

How serious is it? What is the treatment?

Legionnaires' disease can be very serious and can cause death in up to 5% to 30% of cases. Most cases can be treated successfully with antibiotics [drugs that kill bacteria in the body], and healthy people usually recover from infection.

here doLegionella bacteria come from?

The Legionella bacteria are found naturally in the environment, usually in water. The bacteria grow best in warm water, like the kind found in hot tubs, cooling towers, hot water tanks, large plumbing systems, or parts of the air-conditioning systems of large buildings. They do not seem to grow in car or window air-conditioners.

How do people get Legionnaires’ disease?

People get Legionnaires' disease when they breathe in a mist or vapor (small droplets of water in the air) that has been contaminated with the bacteria. One example might be from breathing in the steam from a whirlpool spa that has not been properly cleaned and disinfected.

The bacteria are NOT spread from one person to another person.

Outbreaks are when two or more people become ill in the same place at about the same time, such as patients in hospitals. Hospital buildings have complex water systems, and many people in hospitals already have illnesses that increase their risk for Legionella infection.

Other outbreaks have been linked to aerosol sources in the community, or with cruise ships and hotels, with the most likely sources being whirlpool spas, cooling towers (air-conditioning units from large buildings), and water used for drinking and bathing.

Who gets this disease?

People most at risk of getting sick from the bacteria are older people (usually 65 years of age or older), as well as people who are smokers, or those who have a chronic lung disease (like emphysema).

People who have weak immune systems from diseases like cancer, diabetes, or kidney failure are also more likely to get sick from Legionella bacteria. People who take drugs to suppress (weaken) the immune system (like after a transplant operation or chemotherapy) are also at higher risk.

What should I do if I think I was exposed to Legionella bacteria?

Most people exposed to the bacteria do not become ill. If you have reason to believe you were exposed to the bacteria, talk to your doctor or local health department. Be sure to mention if you have traveled in the last two weeks.

A person diagnosed with Legionnaires’ disease in the workplace is not a threat to others who share office space or other areas with him or her. However, if you believe that there your workplace was the source of the person’s illness, contact your local health department.

Alternative names

Legionella pneumonia; Pontiac fever


Legionnaire's disease is an acute respiratory infection caused by the bacterium Legionella pneumophila, which can cause a broad spectrum of disease from mild cough and fever to a serious pneumonia.

Causes, incidence, and risk factors

The bacteria that cause Legionnaire's disease have been found in water delivery systems and can survive in the warm, moist, air conditioning systems of large buildings including hospitals. The infection is transmitted through the respiratory system. Person-to-person spread has not been proved.

From the onset of symptoms, the condition typically worsens during the first 4 to 6 days, with improvement starting in another 4 to 5 days. Most infection occurs in middle-aged or older people, although it has been reported in children. Typically, the disease is less severe in children.

Risk factors include cigarette smoking; underlying diseases such as renal failure, cancer, diabetes, or chronic obstructive pulmonary disease; people with suppressed immune systems from chemotherapy, steroid medications, or diseases such as cancer and leukemia; alcoholism; being middle-aged or elderly, and in people on a ventilator for extended periods.


<Muscle aches and stiffness
<Joint pain
<Loss of energy
<General discomfort, uneasiness, or ill feeling (malaise)
<Shaking chills
<Nonproductive cough
<Coughing of blood
<Shortness of breath
<Chest pain
<Ataxia (lack of coordination)

Signs and tests

<Listening to the chest with a stethoscope reveals fine crackles.
<Sputum direct fluorescent antibody staining shows Legionella.
<The causative organism may be cultured from the airway.
<Urine tests for the bacteria (urine antigen test) may be positive.
<Chest X-ray shows pneumonia.
<Arterial blood gas analysis may show low concentrations of oxygen.
<CBC shows an increased white blood cell count.
<Erythrocyte sedimentation rate is increased.
<Low serum sodium.
<Liver function tests may show moderate elevation.


The goal of treatment is to eliminate the infection with antibiotics. Treatment is started as soon as Legionnaire's disease is suspected, without waiting for confirmation by culture results.

The antibiotics commonly used are quinolones (ciprofloxacin, levofloxacin, moxifloxacin, or gatifloxacin) or macrolides (azithromycin, clarithromycin, or erythromycin).

Supportive treatment includes hospitalization for fluid and electrolyte replacement and oxygen administration by mask or by mechanical ventilation, if the respiratory system becomes severely compromised by the infection.

Expectations (prognosis)

The overall death rate for those with pneumonia is about 15%, and the death rate increases in those with underlying diseases. The mortality for patients who develop Legionnaire's disease while hospitalized is close to 50%, especially when antibiotics are started late.


Some complications include respiratory failure requiring use of a respirator.

Calling your health care provider

Call your health care provider if breathing difficulties develop.


Active surveillance of infections that were acquired within a hospital can lead to the treatment of contaminated water delivery systems. Detection and treatment of sources outside hospitals usually occurs during or after an epidemic has happened.


Medical Information
It is not the intention of Raptor-Pack to provide specific medical advice but rather to provide users with information to better understand their health and their diagnosed disorders. Specific medical advice will not be provided, and Raptor-Pack urges you to consult with a qualified physician for diagnosis and for answers to your personal questions and specific medical advice




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